Assay Detail
Binding
CHEMBL3705548
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Binding Assay: Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Methods and compositions for sleep disorders and other disorders
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.17 | 9.55 |
Compounds Tested
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL708 | ZIPRASIDONE | Ki | = | 0.28 | nM | 9.55 |
| CHEMBL85 | RISPERIDONE | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL715 | OLANZAPINE | Ki | = | 2.5 | nM | 8.60 |
| CHEMBL1112 | ARIPIPRAZOLE | Ki | = | 9.0 | nM | 8.05 |
| CHEMBL42 | CLOZAPINE | Ki | = | 9.6 | nM | 8.02 |
| CHEMBL54 | HALOPERIDOL | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL716 | QUETIAPINE | Ki | = | 202.0 | nM | 6.70 |