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Assay Detail

CHEMBL3705716

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition Assay: Inhibition assay using human enteropeptidase.
ChEMBL ↗
129
Total Activities
129
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Enteropeptidase (CHEMBL1741195) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Heteroarylcarboxylic acid ester derivative
(2013)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 129 8.98 9.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3639418 — — 1 9.89
CHEMBL3642979 — — 1 9.85
CHEMBL3642960 — — 1 9.68
CHEMBL3642886 — — 1 9.60
CHEMBL3642957 — — 1 9.57
CHEMBL3642902 — — 1 9.55
CHEMBL3642898 — — 1 9.54
CHEMBL3642925 — — 1 9.51
CHEMBL3642948 — — 1 9.51
CHEMBL3642931 — — 1 9.49
CHEMBL3642910 — — 1 9.48
CHEMBL3642947 — — 1 9.48
CHEMBL3642912 — — 1 9.46
CHEMBL3642924 — — 1 9.46
CHEMBL3642958 — — 1 9.43
CHEMBL3642962 — — 1 9.42
CHEMBL3642922 — — 1 9.41
CHEMBL3642968 — — 1 9.41
CHEMBL3642909 — — 1 9.40
CHEMBL3642951 — — 1 9.40
CHEMBL3642965 — — 1 9.39
CHEMBL3642879 — — 1 9.38
CHEMBL3642926 — — 1 9.38
CHEMBL3642899 — — 1 9.38
CHEMBL3642901 — — 1 9.38
CHEMBL3642959 — — 1 9.38
CHEMBL3642911 — — 1 9.34
CHEMBL3642961 — — 1 9.32
CHEMBL3642906 — — 1 9.31
CHEMBL3642882 — — 1 9.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3639418 — Ki = 0.13 nM 9.89
CHEMBL3642979 — Ki = 0.14 nM 9.85
CHEMBL3642960 — Ki = 0.21 nM 9.68
CHEMBL3642886 — Ki = 0.25 nM 9.60
CHEMBL3642957 — Ki = 0.27 nM 9.57
CHEMBL3642902 — Ki = 0.28 nM 9.55
CHEMBL3642898 — Ki = 0.29 nM 9.54
CHEMBL3642948 — Ki = 0.31 nM 9.51
CHEMBL3642925 — Ki = 0.31 nM 9.51
CHEMBL3642931 — Ki = 0.32 nM 9.49
CHEMBL3642910 — Ki = 0.33 nM 9.48
CHEMBL3642947 — Ki = 0.33 nM 9.48
CHEMBL3642924 — Ki = 0.35 nM 9.46
CHEMBL3642912 — Ki = 0.35 nM 9.46
CHEMBL3642958 — Ki = 0.37 nM 9.43
CHEMBL3642962 — Ki = 0.38 nM 9.42
CHEMBL3642922 — Ki = 0.39 nM 9.41
CHEMBL3642968 — Ki = 0.39 nM 9.41
CHEMBL3642951 — Ki = 0.4 nM 9.40
CHEMBL3642909 — Ki = 0.4 nM 9.40
CHEMBL3642965 — Ki = 0.41 nM 9.39
CHEMBL3642879 — Ki = 0.42 nM 9.38
CHEMBL3642926 — Ki = 0.42 nM 9.38
CHEMBL3642899 — Ki = 0.42 nM 9.38
CHEMBL3642901 — Ki = 0.42 nM 9.38
CHEMBL3642959 — Ki = 0.42 nM 9.38
CHEMBL3642911 — Ki = 0.46 nM 9.34
CHEMBL3642961 — Ki = 0.48 nM 9.32
CHEMBL3642906 — Ki = 0.49 nM 9.31
CHEMBL3642904 — Ki = 0.5 nM 9.30
CHEMBL3642953 — Ki = 0.5 nM 9.30
CHEMBL3642882 — Ki = 0.5 nM 9.30
CHEMBL3642907 — Ki = 0.5 nM 9.30
CHEMBL3642952 — Ki = 0.51 nM 9.29
CHEMBL3642928 — Ki = 0.53 nM 9.28
CHEMBL3642932 — Ki = 0.52 nM 9.28
CHEMBL3642946 — Ki = 0.52 nM 9.28
CHEMBL3642978 — Ki = 0.55 nM 9.26
CHEMBL3642903 — Ki = 0.56 nM 9.25
CHEMBL3642878 — Ki = 0.57 nM 9.24
CHEMBL3642977 — Ki = 0.57 nM 9.24
CHEMBL3642970 — Ki = 0.58 nM 9.24
CHEMBL3642945 — Ki = 0.58 nM 9.24
CHEMBL3642887 — Ki = 0.58 nM 9.24
CHEMBL3642889 — Ki = 0.57 nM 9.24
CHEMBL3642919 — Ki = 0.6 nM 9.22
CHEMBL3642861 — Ki = 0.62 nM 9.21
CHEMBL3642883 — Ki = 0.62 nM 9.21
CHEMBL3642870 — Ki = 0.61 nM 9.21
CHEMBL3642888 — Ki = 0.64 nM 9.19