Assay Detail
Binding
CHEMBL3720889
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human T1R1/T1R3 expressed in HEK293T cells co-expressing Galpha15 assessed as reduction in L-glutamate/IMP-induced response in presence of 0.8 mM L-glutamate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.46 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3715108 | LACTISOLE SODIUM | 1.0 | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3715108 | LACTISOLE SODIUM | IC50 | = | 350.0 | nM | 6.46 |