Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3720980

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of N-terminal Flag-tagged mouse TRPM7 expressed in HEK293T cells assessed as reduction in whole cell currents by whole-cell patch clamp assay
14
Total Activities
14
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type HEK-293T
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Agents and methods for treating ischemic and other diseases
(2012)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
INH 13 - -
IC50 1 5.30 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3716072 1 5.30
CHEMBL3717981 1 -
CHEMBL3718897 1 -
CHEMBL3719019 1 -
CHEMBL3716025 1 -
CHEMBL3714873 1 -
CHEMBL3715764 1 -
CHEMBL3715537 1 -
CHEMBL3716221 1 -
CHEMBL3718551 1 -
CHEMBL3717076 1 -
CHEMBL3717768 1 -
CHEMBL3718974 1 -
CHEMBL3718703 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3716072 IC50 = 5000.0 nM 5.30
CHEMBL3717981 INH = 5.0 uM -
CHEMBL3718897 INH = 5.0 uM -
CHEMBL3719019 INH = 5.0 uM -
CHEMBL3716025 INH = 5.0 uM -
CHEMBL3714873 INH = 5.0 uM -
CHEMBL3715764 INH = 5.0 uM -
CHEMBL3715537 INH = 5.0 uM -
CHEMBL3716221 INH = 5.0 uM -
CHEMBL3718551 INH = 5.0 uM -
CHEMBL3717076 INH = 5.0 uM -
CHEMBL3717768 INH = 5.0 uM -
CHEMBL3718974 INH = 5.0 uM -
CHEMBL3718703 INH = 5.0 uM -