Assay Detail
Binding
CHEMBL3721030
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of purified human red blood cell protein phosphatase 2A using DiFMUP substrate incubated for 30 mins
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (CHEMBL4703) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Tautomycetin and Tautomycetin analog biosynthesis
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.90 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1366322 | — | — | 1 | 6.40 |
| CHEMBL3718369 | — | — | 1 | 6.28 |
| CHEMBL3716789 | — | — | 1 | 6.19 |
| CHEMBL3719114 | — | — | 1 | 6.10 |
| CHEMBL3715079 | — | — | 1 | 6.04 |
| CHEMBL3718785 | — | — | 1 | 4.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1366322 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL3718369 | — | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL3716789 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL3719114 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL3715079 | — | IC50 | = | 920.0 | nM | 6.04 |
| CHEMBL3718785 | — | IC50 | = | 44000.0 | nM | 4.36 |