Assay Detail
Functional
CHEMBL3721249
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human A549 cells incubated for 48 hrs by trypan blue dye exclusion assay
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Family of PFKFB3 inhibitors with anti-neoplastic activities
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| GI | 6 | - | - |
| IC50 | 1 | 4.32 | 4.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3105848 | — | — | 1 | 4.32 |
| CHEMBL1390516 | — | — | 1 | - |
| CHEMBL1568243 | — | — | 1 | - |
| CHEMBL3718600 | — | — | 1 | - |
| CHEMBL3714954 | — | — | 1 | - |
| CHEMBL3717152 | — | — | 1 | - |
| CHEMBL1331727 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3105848 | — | IC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL1390516 | — | GI | - | — | - | |
| CHEMBL1568243 | — | GI | - | — | - | |
| CHEMBL3718600 | — | GI | - | — | - | |
| CHEMBL3714954 | — | GI | - | — | - | |
| CHEMBL3717152 | — | GI | - | — | - | |
| CHEMBL1331727 | — | GI | - | — | - |