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Assay Detail

CHEMBL3736639

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of BVDV RNA-dependent RNA polymerase pre-incubated for preincubated for 30 mins before GTP addition and measured after 120 mins by fluorescence based microplate reader assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bovine viral diarrhea virus 1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives.
Briguglio I, Loddo R, Laurini E, Fermeglia M, Piras S, Corona P, Giunchedi P, Gavini E, Sanna G, Giliberti G, Ibba C, Farci P, La Colla P, Pricl S, Carta A.
Eur J Med Chem (2015) 105 : 63 -79
PubMed 26479028 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.19 6.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3735070 1 6.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3735070 IC50 = 640.0 nM 6.19