Assay Detail
Binding
CHEMBL3738575
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human PPAR gamma in human HepG2 cells after 20 hrs by luciferase reporter assay
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Antiviral activity of benzotriazole derivatives. 5-[4-(Benzotriazol-2-yl)phenoxy]-2,2-dimethylpentanoic acids potently and selectively inhibit Coxsackie Virus B5.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 3 | - | - |
| EC50 | 1 | 6.32 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3735011 | — | — | 1 | 6.32 |
| CHEMBL3735292 | — | — | 1 | - |
| CHEMBL3734886 | — | — | 1 | - |
| CHEMBL3734808 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3735011 | — | EC50 | = | 480.0 | nM | 6.32 |
| CHEMBL3735292 | — | Activity | - | — | - | |
| CHEMBL3734886 | — | Activity | - | — | - | |
| CHEMBL3734808 | — | Activity | - | — | - |