Assay Detail
Functional
CHEMBL3738677
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against RSVA2 ATCC VR-1540 infected in african green monkey Vero-76 cells after 5 days by plaque reduction assay
28
Total Activities
28
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Respiratory syncytial virus |
| Cell Type | Vero 76 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Respiratory syncytial virus (CHEMBL612679) ↗| Type | ORGANISM |
| Organism | Respiratory syncytial virus |
Publication
Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 28 | 4.85 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3735511 | — | — | 1 | 5.05 |
| CHEMBL98778 | 2'-ETHYNYL-D-CYTIDINE | — | 1 | 4.64 |
| CHEMBL1940475 | — | — | 1 | - |
| CHEMBL1940472 | — | — | 1 | - |
| CHEMBL3735424 | — | — | 1 | - |
| CHEMBL3735466 | — | — | 1 | - |
| CHEMBL3735224 | — | — | 1 | - |
| CHEMBL3735360 | — | — | 1 | - |
| CHEMBL3734943 | — | — | 1 | - |
| CHEMBL3735842 | — | — | 1 | - |
| CHEMBL3736008 | — | — | 1 | - |
| CHEMBL3735926 | — | — | 1 | - |
| CHEMBL3736028 | — | — | 1 | - |
| CHEMBL3735703 | — | — | 1 | - |
| CHEMBL3734816 | — | — | 1 | - |
| CHEMBL1940474 | — | — | 1 | - |
| CHEMBL3734942 | — | — | 1 | - |
| CHEMBL3734906 | — | — | 1 | - |
| CHEMBL3735971 | — | — | 1 | - |
| CHEMBL3735304 | — | — | 1 | - |
| CHEMBL3735041 | — | — | 1 | - |
| CHEMBL3735827 | — | — | 1 | - |
| CHEMBL3734995 | — | — | 1 | - |
| CHEMBL3735809 | — | — | 1 | - |
| CHEMBL3736323 | — | — | 1 | - |
| CHEMBL3735060 | — | — | 1 | - |
| CHEMBL3735070 | — | — | 1 | - |
| CHEMBL3735085 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3735511 | — | EC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL98778 | 2'-ETHYNYL-D-CYTIDINE | EC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL1940475 | — | EC50 | > | 88000.0 | nM | - |
| CHEMBL1940472 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735424 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735466 | — | EC50 | > | 90000.0 | nM | - |
| CHEMBL3735224 | — | EC50 | > | 35000.0 | nM | - |
| CHEMBL3735360 | — | EC50 | > | 25000.0 | nM | - |
| CHEMBL3734943 | — | EC50 | > | 15000.0 | nM | - |
| CHEMBL3735842 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL3736008 | — | EC50 | > | 70000.0 | nM | - |
| CHEMBL3735926 | — | EC50 | > | 20000.0 | nM | - |
| CHEMBL3736028 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735703 | — | EC50 | > | 20000.0 | nM | - |
| CHEMBL3734816 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL1940474 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3734942 | — | EC50 | > | 90000.0 | nM | - |
| CHEMBL3734906 | — | EC50 | > | 90000.0 | nM | - |
| CHEMBL3735971 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735304 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL3735041 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735827 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3734995 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735809 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3736323 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735060 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735070 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL3735085 | — | EC50 | > | 60000.0 | nM | - |