Assay Detail
Functional
CHEMBL3738682
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Antiviral activity against Hepatitis C virus genotype 1b replicon infected in human GS4.1 cells assessed as protection against virus-induced cytopathic effect after 72 days by ELISA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.12 | 5.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3735424 | — | — | 1 | 5.12 |
| CHEMBL1940474 | — | — | 1 | - |
| CHEMBL1940475 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3735424 | — | EC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL1940474 | — | EC50 | > | 11000.0 | nM | - |
| CHEMBL1940475 | — | EC50 | > | 65000.0 | nM | - |