Assay Detail
Functional
CHEMBL3742733
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Antiprotozoal activity against Entamoeba histolytica HM-1:IMSS
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Entamoeba histolytica |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
ent-Kaurene Glycosides from Ageratina cylindrica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.90 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137 | METRONIDAZOLE | 4.0 | 1 | 6.64 |
| CHEMBL50588 | EMETINE | 4.0 | 1 | 5.66 |
| CHEMBL3742123 | — | — | 1 | 4.36 |
| CHEMBL3741211 | — | — | 1 | 4.30 |
| CHEMBL3739562 | — | — | 1 | 4.28 |
| CHEMBL3739801 | — | — | 1 | 4.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137 | METRONIDAZOLE | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL50588 | EMETINE | IC50 | = | 2180.0 | nM | 5.66 |
| CHEMBL3742123 | — | IC50 | = | 43300.0 | nM | 4.36 |
| CHEMBL3741211 | — | IC50 | = | 49500.0 | nM | 4.30 |
| CHEMBL3739562 | — | IC50 | = | 52700.0 | nM | 4.28 |
| CHEMBL3739801 | — | IC50 | = | 73500.0 | nM | 4.13 |