Assay Detail
Functional
CHEMBL3742981
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Antibiofilm activity against Pseudoalteromonas lipolytica TC8 assessed as reduction in adhesion after 15 hrs by Syto61 based-fluorescence analysis relative to control
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Pseudoalteromonas lipolytica |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Pseudoalteromonas lipolytica (CHEMBL4296594) ↗| Type | ORGANISM |
| Organism | Pseudoalteromonas lipolytica |
Publication
Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 4.31 | 4.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL174 | AMPICILLIN | 4.0 | 1 | 4.75 |
| CHEMBL3739616 | — | — | 1 | 4.17 |
| CHEMBL3739688 | — | — | 1 | 4.02 |
| CHEMBL3741233 | — | — | 1 | - |
| CHEMBL3739976 | — | — | 1 | - |
| CHEMBL3742346 | — | — | 1 | - |
| CHEMBL3739635 | — | — | 1 | - |
| CHEMBL3741894 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL174 | AMPICILLIN | EC50 | = | 17900.0 | nM | 4.75 |
| CHEMBL3739616 | — | EC50 | = | 67800.0 | nM | 4.17 |
| CHEMBL3739688 | — | EC50 | = | 96000.0 | nM | 4.02 |
| CHEMBL3741233 | — | EC50 | = | 123600.0 | nM | - |
| CHEMBL3739976 | — | EC50 | = | 170500.0 | nM | - |
| CHEMBL3742346 | — | EC50 | = | 113200.0 | nM | - |
| CHEMBL3739635 | — | EC50 | = | 104400.0 | nM | - |
| CHEMBL3741894 | — | EC50 | = | 134200.0 | nM | - |