Assay Detail
Functional
CHEMBL3743412
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Antifungal activity against Candida albicans SC5314 assessed as inhibition of yeast to hyphae conversion after 4 hrs by microscopic analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive ent-Pimarane and ent-Abietane Diterpenoids from the Whole Plants of Chloranthus henryi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.57 | 5.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL180920 | MAGNOLOL | — | 1 | 5.12 |
| CHEMBL3739708 | — | — | 1 | 4.01 |
| CHEMBL3739719 | — | — | 1 | - |
| CHEMBL3740782 | — | — | 1 | - |
| CHEMBL3742231 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL180920 | MAGNOLOL | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL3739708 | — | IC50 | = | 97300.0 | nM | 4.01 |
| CHEMBL3739719 | — | IC50 | = | 333700.0 | nM | - |
| CHEMBL3740782 | — | IC50 | = | 399000.0 | nM | - |
| CHEMBL3742231 | — | IC50 | = | 738700.0 | nM | - |