Assay Detail
Binding
CHEMBL3744512
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]prazosin from human recombinant alpha1D adrenoceptor expressed in CHO cell membrane after 30 mins by liquid scintillation counting
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent 1and 5-HT1Areceptor ligand: an in vitro and computational study
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.14 | 9.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3741808 | — | — | 1 | 9.29 |
| CHEMBL3740374 | — | — | 1 | 7.98 |
| CHEMBL37883 | — | — | 1 | 7.93 |
| CHEMBL3739932 | — | — | 1 | 7.84 |
| CHEMBL3739897 | — | — | 1 | 7.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3741808 | — | Ki | = | 0.5129 | nM | 9.29 |
| CHEMBL3740374 | — | Ki | = | 10.47 | nM | 7.98 |
| CHEMBL37883 | — | Ki | = | 11.75 | nM | 7.93 |
| CHEMBL3739932 | — | Ki | = | 14.45 | nM | 7.84 |
| CHEMBL3739897 | — | Ki | = | 22.91 | nM | 7.64 |