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Assay Detail

CHEMBL3744528

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of HBV DNA replication in HepG2 cells by southern blot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Hepatitis B virus
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

Hepatitis B virus (CHEMBL613497)
Type ORGANISM
Organism Hepatitis B virus

Publication

Non-nucleoside anti-HBV agents: advances in structural optimization and mechanism of action investigations
Liu N, Zhao F, Jia H, Rai D, Zhan P, Jiang X, Liu X
Medchemcomm (2015) 6 : 521 -535
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.92 7.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3742114 1 7.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3742114 IC50 = 12.0 nM 7.92