Assay Detail
Functional
CHEMBL3745112
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Cytotoxicity against human MCF7 cells assessed as cell death after 24 hrs by MTT assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An efficient green synthesis of 2-arylbenzothiazole analogues as potent antibacterial and anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.75 | 5.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3739816 | — | — | 1 | 5.03 |
| CHEMBL1908905 | — | — | 1 | 5.01 |
| CHEMBL3741446 | — | — | 1 | 4.98 |
| CHEMBL3742408 | — | — | 1 | 4.97 |
| CHEMBL1717340 | — | — | 1 | 4.75 |
| CHEMBL2272273 | 2-PHENYLBENZO[D]THIAZOLE | — | 1 | 4.73 |
| CHEMBL1808307 | — | — | 1 | 4.69 |
| CHEMBL1379011 | — | — | 1 | 4.69 |
| CHEMBL1491251 | — | — | 1 | 4.65 |
| CHEMBL1650632 | — | — | 1 | 4.57 |
| CHEMBL1509336 | — | — | 1 | 4.54 |
| CHEMBL1808306 | — | — | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3739816 | — | IC50 | = | 9260.0 | nM | 5.03 |
| CHEMBL1908905 | — | IC50 | = | 9850.0 | nM | 5.01 |
| CHEMBL3741446 | — | IC50 | = | 10500.0 | nM | 4.98 |
| CHEMBL3742408 | — | IC50 | = | 10650.0 | nM | 4.97 |
| CHEMBL1717340 | — | IC50 | = | 17620.0 | nM | 4.75 |
| CHEMBL2272273 | 2-PHENYLBENZO[D]THIAZOLE | IC50 | = | 18500.0 | nM | 4.73 |
| CHEMBL1808307 | — | IC50 | = | 20450.0 | nM | 4.69 |
| CHEMBL1379011 | — | IC50 | = | 20420.0 | nM | 4.69 |
| CHEMBL1491251 | — | IC50 | = | 22600.0 | nM | 4.65 |
| CHEMBL1650632 | — | IC50 | = | 26800.0 | nM | 4.57 |
| CHEMBL1509336 | — | IC50 | = | 28600.0 | nM | 4.54 |
| CHEMBL1808306 | — | IC50 | = | 42280.0 | nM | 4.37 |