Assay Detail
Functional
CHEMBL3745113
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HeLa cells assessed as cell death after 24 hrs by MTT assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
An efficient green synthesis of 2-arylbenzothiazole analogues as potent antibacterial and anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.62 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3739816 | — | — | 1 | 4.82 |
| CHEMBL1908905 | — | — | 1 | 4.78 |
| CHEMBL3741446 | — | — | 1 | 4.76 |
| CHEMBL3742408 | — | — | 1 | 4.74 |
| CHEMBL2272273 | 2-PHENYLBENZO[D]THIAZOLE | — | 1 | 4.66 |
| CHEMBL1717340 | — | — | 1 | 4.65 |
| CHEMBL1379011 | — | — | 1 | 4.56 |
| CHEMBL1808307 | — | — | 1 | 4.55 |
| CHEMBL1491251 | — | — | 1 | 4.55 |
| CHEMBL1650632 | — | — | 1 | 4.51 |
| CHEMBL1509336 | — | — | 1 | 4.49 |
| CHEMBL1808306 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3739816 | — | IC50 | = | 15210.0 | nM | 4.82 |
| CHEMBL1908905 | — | IC50 | = | 16600.0 | nM | 4.78 |
| CHEMBL3741446 | — | IC50 | = | 17400.0 | nM | 4.76 |
| CHEMBL3742408 | — | IC50 | = | 18220.0 | nM | 4.74 |
| CHEMBL2272273 | 2-PHENYLBENZO[D]THIAZOLE | IC50 | = | 22120.0 | nM | 4.66 |
| CHEMBL1717340 | — | IC50 | = | 22620.0 | nM | 4.65 |
| CHEMBL1379011 | — | IC50 | = | 27500.0 | nM | 4.56 |
| CHEMBL1808307 | — | IC50 | = | 28250.0 | nM | 4.55 |
| CHEMBL1491251 | — | IC50 | = | 28460.0 | nM | 4.55 |
| CHEMBL1650632 | — | IC50 | = | 30600.0 | nM | 4.51 |
| CHEMBL1509336 | — | IC50 | = | 32600.0 | nM | 4.49 |
| CHEMBL1808306 | — | IC50 | = | 48200.0 | nM | 4.32 |