Assay Detail
Binding
CHEMBL3745367
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Reversible inhibition of human MAO-B
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.46 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL126 | LINEZOLID | 4.0 | 1 | 5.68 |
| CHEMBL1257051 | TEDIZOLID | 3.0 | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL126 | LINEZOLID | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL1257051 | TEDIZOLID | IC50 | = | 5700.0 | nM | 5.24 |