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Assay Detail

CHEMBL3748314

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibiofilm activity against Bacillus subtilis MTCC 121 after 24 hrs by well diffusion assay by crystal violet staining based method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Bacillus subtilis
Confidence 1 — Organism
Curated By Autocuration

Target

Bacillus subtilis (CHEMBL359)
Type ORGANISM
Organism Bacillus subtilis

Publication

Synthesis and biological evaluation of novel lipoamino acid derivatives.
Kaki SS, Arukali S, Korlipara PV, Prasad RB, Yedla P, Ganesh Kumar C.
Bioorg Med Chem Lett (2016) 26 : 209 -212
PubMed 26586599 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.73 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL8 CIPROFLOXACIN 4.0 1 6.30
CHEMBL3747174 1 5.72
CHEMBL3747025 1 5.55
CHEMBL3746340 1 5.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL8 CIPROFLOXACIN IC50 = 500.0 nM 6.30
CHEMBL3747174 IC50 = 1900.0 nM 5.72
CHEMBL3747025 IC50 = 2800.0 nM 5.55
CHEMBL3746340 IC50 = 4400.0 nM 5.36