Assay Detail
Functional
CHEMBL3748331
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Cytotoxicity against human MDA-MB-231 cells by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel lipoamino acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.75 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.16 |
| CHEMBL3747292 | — | — | 1 | 4.65 |
| CHEMBL3746340 | — | — | 1 | 4.50 |
| CHEMBL3746346 | — | — | 1 | 4.41 |
| CHEMBL3747025 | — | — | 1 | 4.01 |
| CHEMBL3746616 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL3747292 | — | IC50 | = | 22400.0 | nM | 4.65 |
| CHEMBL3746340 | — | IC50 | = | 31400.0 | nM | 4.50 |
| CHEMBL3746346 | — | IC50 | = | 38600.0 | nM | 4.41 |
| CHEMBL3747025 | — | IC50 | = | 98700.0 | nM | 4.01 |
| CHEMBL3746616 | — | IC50 | = | 152100.0 | nM | - |