Assay Detail
Binding
CHEMBL3756283
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to 5-HT 6 (unknown origin) by competition binding assay
12
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Receptor binding profiles and quantitative structure-affinity relationships of some 5-substituted-N,N-diallyltryptamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 12 | 6.65 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3752900 | — | — | 2 | 7.16 |
| CHEMBL3754496 | — | — | 2 | 7.13 |
| CHEMBL3754166 | — | — | 2 | 6.88 |
| CHEMBL2391541 | — | — | 2 | 6.81 |
| CHEMBL3753318 | — | — | 2 | 6.13 |
| CHEMBL3752576 | — | — | 2 | 5.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3752900 | — | Ki | = | 69.18 | nM | 7.16 |
| CHEMBL3754496 | — | Ki | = | 74.13 | nM | 7.13 |
| CHEMBL3754166 | — | Ki | = | 131.83 | nM | 6.88 |
| CHEMBL2391541 | — | Ki | = | 154.88 | nM | 6.81 |
| CHEMBL3753318 | — | Ki | = | 741.31 | nM | 6.13 |
| CHEMBL3752576 | — | Ki | = | 1737.8 | nM | 5.76 |
| CHEMBL3753318 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL2391541 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3752576 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3754496 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3752900 | — | Ki | < | 10000.0 | nM | - |
| CHEMBL3754166 | — | Ki | < | 10000.0 | nM | - |