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Assay Detail

CHEMBL3756443

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of serum-opsonized zymosan-induced oxidative burst in whole blood (unknown origin)
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Not specified
Tissue Blood
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Oxidative burst inhibition, cytotoxicity and antibacterial acriquinoline alkaloids from Citrus reticulate (Blanco).
Fomani M, Ngeufa Happi E, Nouga Bisoue A, Ndom JC, Kamdem Waffo AF, Sewald N, Wansi JD.
Bioorg Med Chem Lett (2016) 26 : 306 -309
PubMed 26711890 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 9 4.92 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3754791 1 5.35
CHEMBL140796 ISOPIMPINELLIN 1 5.03
CHEMBL465808 ATALANTOFLAVONE 1 4.98
CHEMBL521 IBUPROFEN 4.0 1 4.95
CHEMBL325864 SCOPARONE 1 4.94
CHEMBL3753940 1 4.79
CHEMBL3752565 1 4.76
CHEMBL1928409 SUBEROSIN 1 4.74
CHEMBL3752540 1 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3754791 IC50 = 4500.0 nM 5.35
CHEMBL140796 ISOPIMPINELLIN IC50 = 9400.0 nM 5.03
CHEMBL465808 ATALANTOFLAVONE IC50 = 10500.0 nM 4.98
CHEMBL521 IBUPROFEN IC50 = 11200.0 nM 4.95
CHEMBL325864 SCOPARONE IC50 = 11400.0 nM 4.94
CHEMBL3753940 IC50 = 16400.0 nM 4.79
CHEMBL3752565 IC50 = 17200.0 nM 4.76
CHEMBL1928409 SUBEROSIN IC50 = 18300.0 nM 4.74
CHEMBL3752540 IC50 = 20100.0 nM 4.70