Assay Detail
Binding
CHEMBL3756498
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Binding affinity to DAT (unknown origin) by competition binding assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium-dependent dopamine transporter (CHEMBL238) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Receptor binding profiles and quantitative structure-affinity relationships of some 5-substituted-N,N-diallyltryptamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.72 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3752900 | — | — | 1 | 6.10 |
| CHEMBL3752576 | — | — | 1 | 5.90 |
| CHEMBL3754496 | — | — | 1 | 5.70 |
| CHEMBL3754166 | — | — | 1 | 5.60 |
| CHEMBL2391541 | — | — | 1 | 5.50 |
| CHEMBL3753318 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3752900 | — | Ki | = | 794.33 | nM | 6.10 |
| CHEMBL3752576 | — | Ki | = | 1258.93 | nM | 5.90 |
| CHEMBL3754496 | — | Ki | = | 1995.26 | nM | 5.70 |
| CHEMBL3754166 | — | Ki | = | 2511.89 | nM | 5.60 |
| CHEMBL2391541 | — | Ki | = | 3162.28 | nM | 5.50 |
| CHEMBL3753318 | — | Ki | = | 3162.28 | nM | 5.50 |