Assay Detail
Binding
CHEMBL3756508
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Competitive inhibition of Escherichia coli beta-galactosidase assessed as p-nitrophenyl-beta-D-galactopyranoside substrate hydrolysis by UV/Vis spectroscopy
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Illuminating the binding interactions of galactonoamidines during the inhibition of β-galactosidase (E. coli).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.50 | 10.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3359672 | — | — | 1 | 10.22 |
| CHEMBL3752112 | — | — | 1 | 8.89 |
| CHEMBL3753015 | — | — | 1 | 7.50 |
| CHEMBL3754250 | — | — | 1 | 7.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3359672 | — | Ki | = | 0.06 | nM | 10.22 |
| CHEMBL3752112 | — | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL3753015 | — | Ki | = | 32.0 | nM | 7.50 |
| CHEMBL3754250 | — | Ki | = | 42.0 | nM | 7.38 |