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Assay Detail

CHEMBL3756613

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Transactivation of human PPARdelta expressed in HEK293 cells incubated for 18 hrs by dual luciferase reporter gene assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Peroxisome proliferator-activated receptor delta (CHEMBL3979)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PPAR agonists based on stilbene and its bioisosteres: biological evaluation and docking studies
De Filippis B, Agamennone M, Ammazzalorso A, Bruno I, D'Angelo A, Di Matteo M, Fantacuzzi M, Giampietro L, Giancristofaro A, Maccallini C, Amoroso R
Medchemcomm (2015) 6 : 1513 -1517
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.68 7.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL153057 1 7.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL153057 EC50 = 21.0 nM 7.68