Assay Detail
Binding
CHEMBL3756955
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of human aromatase extracted from placental microsomes in presence of androstenedione
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Developing steroidal aromatase inhibitors-an effective armament to win the battle against breast cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.17 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3752770 | — | — | 1 | 8.70 |
| CHEMBL3753593 | — | — | 1 | 8.00 |
| CHEMBL1078534 | ANDROSTENEDONE | — | 1 | 6.58 |
| CHEMBL209073 | — | — | 1 | 6.58 |
| CHEMBL3085491 | — | — | 1 | 6.58 |
| CHEMBL3752359 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3752770 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL3753593 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL1078534 | ANDROSTENEDONE | Ki | = | 260.0 | nM | 6.58 |
| CHEMBL209073 | — | Ki | = | 260.0 | nM | 6.58 |
| CHEMBL3085491 | — | Ki | = | 260.0 | nM | 6.58 |
| CHEMBL3752359 | — | Ki | = | 260.0 | nM | 6.58 |