Assay Detail
ADMET
CHEMBL3757731
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Cytotoxicity against African green monkey Vero cells after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.26 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3751862 | — | — | 1 | 5.52 |
| CHEMBL3752490 | — | — | 1 | 5.36 |
| CHEMBL3753581 | — | — | 1 | 5.35 |
| CHEMBL3754495 | — | — | 1 | 4.82 |
| CHEMBL3752598 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3751862 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3752490 | — | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL3753581 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL3754495 | — | IC50 | = | 15200.0 | nM | 4.82 |
| CHEMBL3752598 | — | IC50 | = | 454700.0 | nM | - |