Assay Detail
Binding
CHEMBL3757845
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]MRE3008-F20 from human A3 receptor expressed in CHO cells by scintillation counter
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
5,7-Disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazines as pharmacological tools to explore the antagonist selectivity profiles toward adenosine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.16 | 9.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL324735 | — | — | 1 | 9.80 |
| CHEMBL342059 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL324735 | — | Ki | = | 0.16 | nM | 9.80 |
| CHEMBL342059 | — | Ki | = | 300.0 | nM | 6.52 |