Assay Detail
Binding
CHEMBL3757882
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Binding affinity to human cloned D5 dopamine receptor incubated for 90 mins by radioligand binding assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
D1-like receptors distinguishing thieno-azecine regioisomers
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 8.33 | 8.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL201170 | — | — | 1 | 8.82 |
| CHEMBL3753266 | — | — | 1 | 8.72 |
| CHEMBL3752512 | — | — | 1 | 8.52 |
| CHEMBL441618 | — | — | 1 | 8.12 |
| CHEMBL201525 | — | — | 1 | 7.95 |
| CHEMBL201093 | — | — | 1 | 7.82 |
| CHEMBL3752882 | — | — | 1 | - |
| CHEMBL3753195 | — | — | 1 | - |
| CHEMBL3754576 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL201170 | — | Ki | = | 1.5 | nM | 8.82 |
| CHEMBL3753266 | — | Ki | = | 1.9 | nM | 8.72 |
| CHEMBL3752512 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL441618 | — | Ki | = | 7.5 | nM | 8.12 |
| CHEMBL201525 | — | Ki | = | 11.2 | nM | 7.95 |
| CHEMBL201093 | — | Ki | = | 15.0 | nM | 7.82 |
| CHEMBL3752882 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL3753195 | — | Ki | > | 1000.0 | nM | - |
| CHEMBL3754576 | — | Ki | > | 1000.0 | nM | - |