Assay Detail
Binding
CHEMBL3757902
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Binding affinity to human CDK2 by isothermal titration calorimetric analysis
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of new hit scaffolds by INPHARMA-guided virtual screening
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 4.34 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL476189 | — | — | 1 | 4.46 |
| CHEMBL228862 | 6-BENZYLAMINOPURINE | — | 1 | 4.21 |
| CHEMBL477 | ADENOSINE | 4.0 | 1 | - |
| CHEMBL143054 | — | — | 1 | - |
| CHEMBL38380 | FASUDIL | 3.0 | 1 | - |
| CHEMBL3754754 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL476189 | — | Kd | = | 35000.0 | nM | 4.46 |
| CHEMBL228862 | 6-BENZYLAMINOPURINE | Kd | = | 62000.0 | nM | 4.21 |
| CHEMBL477 | ADENOSINE | Kd | = | 184000.0 | nM | - |
| CHEMBL143054 | — | Kd | = | 286000.0 | nM | - |
| CHEMBL38380 | FASUDIL | Kd | = | 460000.0 | nM | - |
| CHEMBL3754754 | — | Kd | = | 208000.0 | nM | - |