Assay Detail
Binding
CHEMBL3762584
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Binding affinity to kappa opioid receptor (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Multitarget opioid ligands in pain relief: New players in an old game.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 8.99 | 10.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301160 | BUTORPHAN | — | 1 | 10.14 |
| CHEMBL3759238 | — | — | 1 | 9.74 |
| CHEMBL3758259 | — | — | 1 | 8.89 |
| CHEMBL583066 | — | — | 1 | 8.60 |
| CHEMBL326684 | — | — | 1 | 7.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301160 | BUTORPHAN | Ki | = | 0.073 | nM | 10.14 |
| CHEMBL3759238 | — | Ki | = | 0.18 | nM | 9.74 |
| CHEMBL3758259 | — | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL583066 | — | Ki | = | 2.5 | nM | 8.60 |
| CHEMBL326684 | — | Ki | = | 25.2 | nM | 7.60 |