Assay Detail
Binding
CHEMBL3766609
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine tubulin assembly after 15 mins by turbidimetric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.40 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3764535 | — | — | 1 | 6.60 |
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 6.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3764535 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 650.0 | nM | 6.19 |