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Assay Detail

CHEMBL3766977

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HIV-1 reverse transcriptase using and rCdC as template and tritium-labeled dGTP incubated for 30 mins by liquid scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 1
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Human immunodeficiency virus type 1 reverse transcriptase (CHEMBL247)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

Recent developments of 2-aminothiazoles in medicinal chemistry.
Das D, Sikdar P, Bairagi M.
Eur J Med Chem (2016) 109 : 89 -98
PubMed 26771245 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.05 6.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL33981 1 6.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL33981 IC50 = 900.0 nM 6.05