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Assay Detail

CHEMBL3768094

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human CRBN (delta 1 to 315) by FRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Protein cereblon (CHEMBL3763008)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A FRET-Based Assay for the Identification and Characterization of Cereblon Ligands.
Boichenko I, Deiss S, Bär K, Hartmann MD, Hernandez Alvarez B.
J Med Chem (2016) 59 : 770 -774
PubMed 26730808 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.10 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3764647 1 5.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3764647 Kd = 7900.0 nM 5.10