Assay Detail
Binding
CHEMBL3768233
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant COX-2 using arachidonic acid as substrate assessed as PGE2 production preincubated for 10 mins followed by substrate addition incubated for 2 mins by ELISA
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Anti-inflammatory and antioxidant properties of a novel resveratrol-salicylate hybrid analog.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.69 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 6.00 |
| CHEMBL3765737 | — | — | 1 | 6.00 |
| CHEMBL296411 | TRISMETHOXYRESVERATROL | — | 1 | 5.78 |
| CHEMBL3763742 | — | — | 1 | 4.99 |
| CHEMBL1095380 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL165 | RESVERATROL | IC50 | = | 996.0 | nM | 6.00 |
| CHEMBL3765737 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL296411 | TRISMETHOXYRESVERATROL | IC50 | = | 1667.0 | nM | 5.78 |
| CHEMBL3763742 | — | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL1095380 | — | IC50 | > | 500000.0 | nM | - |