Assay Detail
Binding
CHEMBL3768249
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Binding affinity to recombinant 5-HT7 receptor (unknown origin) after 1.5 hrs by radioligand displacement assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel N-acyl-carbazole derivatives as 5-HT7R antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.29 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3763779 | — | — | 1 | 7.52 |
| CHEMBL3764335 | — | — | 1 | 7.42 |
| CHEMBL3764650 | — | — | 1 | 7.13 |
| CHEMBL3764133 | — | — | 1 | 7.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3763779 | — | Ki | = | 30.0 | nM | 7.52 |
| CHEMBL3764335 | — | Ki | = | 38.0 | nM | 7.42 |
| CHEMBL3764650 | — | Ki | = | 74.0 | nM | 7.13 |
| CHEMBL3764133 | — | Ki | = | 86.0 | nM | 7.07 |