Assay Detail
Binding
CHEMBL3768262
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Binding affinity to recombinant 5-HT2C receptor (unknown origin) after 1.5 hrs by radioligand displacement assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel N-acyl-carbazole derivatives as 5-HT7R antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.96 | 6.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3764650 | — | — | 1 | 6.23 |
| CHEMBL3763779 | — | — | 1 | 5.93 |
| CHEMBL3764335 | — | — | 1 | 5.86 |
| CHEMBL3764133 | — | — | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3764650 | — | Ki | = | 588.0 | nM | 6.23 |
| CHEMBL3763779 | — | Ki | = | 1174.0 | nM | 5.93 |
| CHEMBL3764335 | — | Ki | = | 1393.0 | nM | 5.86 |
| CHEMBL3764133 | — | Ki | = | 1519.0 | nM | 5.82 |