Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3768615

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human NEK6
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Serine/threonine-protein kinase Nek6 (CHEMBL4309)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents.
Min J, Guo K, Suryadevara PK, Zhu F, Holbrook G, Chen Y, Feau C, Young BM, Lemoff A, Connelly MC, Kastan MB, Guy RK.
J Med Chem (2016) 59 : 559 -577
PubMed 26632965 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3763358 1 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3763358 Kd = 130.0 nM 6.89