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Assay Detail

CHEMBL3771485

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Binding
Binding affinity to partial length human BRD7 by BROMOscan assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Bromodomain-containing protein 7 (CHEMBL3085622)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
Theodoulou NH, Bamborough P, Bannister AJ, Becher I, Bit RA, Che KH, Chung CW, Dittmann A, Drewes G, Drewry DH, Gordon L, Grandi P, Leveridge M, Lindon M, Michon AM, Molnar J, Robson SC, Tomkinson NC, Kouzarides T, Prinjha RK, Humphreys PG.
J Med Chem (2016) 59 : 1425 -1439
PubMed 25856009 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.40 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3769507 1 6.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3769507 Kd = 398.11 nM 6.40