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Assay Detail

CHEMBL3772887

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Influenza A virus A/WSN/33 (H1N1) HA1 protein by surface plasmon resonance assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Influenza A virus (A/WSN/1933(H1N1))
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Spiromastilactones: A new class of influenza virus inhibitors from deep-sea fungus.
Niu S, Si L, Liu D, Zhou A, Zhang Z, Shao Z, Wang S, Zhang L, Zhou D, Lin W.
Eur J Med Chem (2016) 108 : 229 -244
PubMed 26686929 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 4.70 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3770799 1 5.22
CHEMBL3770267 1 4.94
CHEMBL3770699 1 4.51
CHEMBL3770809 1 4.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3770799 IC50 = 6000.0 nM 5.22
CHEMBL3770267 IC50 = 11400.0 nM 4.94
CHEMBL3770699 IC50 = 30700.0 nM 4.51
CHEMBL3770809 IC50 = 74900.0 nM 4.13