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Assay Detail

CHEMBL3774072

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Binding
Inhibition of green coffee bean alpha-galactosidase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Coffea arabica
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful β-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomal β-galactosidase.
Thonhofer M, Weber P, Santana AG, Fischer R, Pabst BM, Paschke E, Schalli M, Stütz AE, Tschernutter M, Windischhofer W, Withers SG.
Bioorg Med Chem Lett (2016) 26 : 1438 -1442
PubMed 26838810 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.51 5.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1922581 1 5.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1922581 Ki = 3100.0 nM 5.51