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Assay Detail

CHEMBL3777309

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]AVP from human Vasopressin V2 receptor expressed in HeLa cells after 2 hrs by liquid scintillation counter
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HeLa
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Vasopressin V2 receptor (CHEMBL1790)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Tactical Approaches to Interconverting GPCR Agonists and Antagonists.
Dosa PI, Amin EA.
J Med Chem (2016) 59 : 810 -840
PubMed 26390077 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.75 7.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL334376 1 7.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL334376 IC50 = 18.0 nM 7.75