Assay Detail
Binding
CHEMBL3777321
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Binding affinity to Adenosine receptor A3 (unknown origin)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tactical Approaches to Interconverting GPCR Agonists and Antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.09 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL431733 | NAMODENOSON | 3.0 | 1 | 8.85 |
| CHEMBL307199 | — | — | 1 | 8.74 |
| CHEMBL119709 | IB-MECA | — | 1 | 8.74 |
| CHEMBL66393 | — | — | 1 | 8.24 |
| CHEMBL2181969 | — | — | 1 | 7.53 |
| CHEMBL284969 | — | — | 1 | 7.42 |
| CHEMBL68738 | N6-CYCLOPENTYLADENOSINE | — | 1 | 7.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL431733 | NAMODENOSON | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL307199 | — | Ki | = | 1.8 | nM | 8.74 |
| CHEMBL119709 | IB-MECA | Ki | = | 1.8 | nM | 8.74 |
| CHEMBL66393 | — | Ki | = | 5.8 | nM | 8.24 |
| CHEMBL2181969 | — | Ki | = | 29.3 | nM | 7.53 |
| CHEMBL284969 | — | Ki | = | 38.0 | nM | 7.42 |
| CHEMBL68738 | N6-CYCLOPENTYLADENOSINE | Ki | = | 72.0 | nM | 7.14 |