Assay Detail
Binding
CHEMBL3777322
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Displacement of [3H]BK from cloned human B2 bradykinin receptor expressed in CHO cells after 2 hrs by liquid scintillation counter
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tactical Approaches to Interconverting GPCR Agonists and Antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.82 | 9.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3774617 | — | — | 1 | 9.44 |
| CHEMBL99869 | — | — | 1 | 9.39 |
| CHEMBL439737 | — | — | 1 | 8.96 |
| CHEMBL1195824 | — | — | 1 | 7.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3774617 | — | IC50 | = | 0.36 | nM | 9.44 |
| CHEMBL99869 | — | IC50 | = | 0.41 | nM | 9.39 |
| CHEMBL439737 | — | IC50 | = | 1.1 | nM | 8.96 |
| CHEMBL1195824 | — | IC50 | = | 34.0 | nM | 7.47 |