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Assay Detail

CHEMBL3778347

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]-dihydro-bevirimat from HIV1 Gag polyprotein virus like particles after 3 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

C-3 benzoic acid derivatives of C-3 deoxybetulinic acid and deoxybetulin as HIV-1 maturation inhibitors.
Liu Z, Swidorski JJ, Nowicka-Sans B, Terry B, Protack T, Lin Z, Samanta H, Zhang S, Li Z, Parker DD, Rahematpura S, Jenkins S, Beno BR, Krystal M, Meanwell NA, Dicker IB, Regueiro-Ren A.
Bioorg Med Chem (2016) 24 : 1757 -1770
PubMed 26968652 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.57 7.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3775172 1 7.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3775172 IC50 = 27.0 nM 7.57