Assay Detail
Functional
CHEMBL3782199
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antioxidant activity in human HepG2 cells assessed as decrease in fluorescence level after 2.5 hrs measured every 5 mins for 1 hr by DCFH-DA staining based fluorescence assay
4
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Protective effects of kaempferol against reactive oxygen species-induced hemolysis and its antiproliferative activity on human cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.18 | 5.33 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.33 |
| CHEMBL150 | KAEMPFEROL | 1.0 | 2 | 5.11 |
| CHEMBL90568 | DIOSMETIN | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | EC50 | = | 4630.0 | nM | 5.33 |
| CHEMBL150 | KAEMPFEROL | EC50 | = | 7740.0 | nM | 5.11 |
| CHEMBL90568 | DIOSMETIN | EC50 | = | 7980.0 | nM | 5.10 |
| CHEMBL150 | KAEMPFEROL | Activity | - | — | - |