Assay Detail
Functional
CHEMBL3782489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Human coxsackievirus B2 infected in african green monkey Vero cells after 24 to 36 hrs by MTS-based CPE reduction assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Coxsackievirus B2 |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification and Structure-Activity Relationships of Diarylhydrazides as Novel Potent and Selective Human Enterovirus Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.95 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3779938 | — | — | 1 | 9.30 |
| CHEMBL3781846 | — | — | 1 | 9.05 |
| CHEMBL3780944 | — | — | 1 | 8.80 |
| CHEMBL283403 | ENVIROXIME | 2.0 | 1 | 6.82 |
| CHEMBL3781624 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3779938 | — | EC50 | = | 0.5 | nM | 9.30 |
| CHEMBL3781846 | — | EC50 | = | 0.9 | nM | 9.05 |
| CHEMBL3780944 | — | EC50 | = | 1.6 | nM | 8.80 |
| CHEMBL283403 | ENVIROXIME | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL3781624 | — | EC50 | = | 1570.0 | nM | 5.80 |