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Assay Detail

CHEMBL3783544

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to dopamine D3 receptor (unknown origin) by PDSP assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

D(3) dopamine receptor (CHEMBL234)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Tetrahydroprotoberberine alkaloids with dopamine and σ receptor affinity.
Gadhiya S, Madapa S, Kurtzman T, Alberts IL, Ramsey S, Pillarsetty NK, Kalidindi T, Harding WW.
Bioorg Med Chem (2016) 24 : 2060 -2071
PubMed 27032890 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL487387 STEPHOLIDINE 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL487387 STEPHOLIDINE Ki = 30.0 nM 7.52