Assay Detail
Binding
CHEMBL3784037
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cynomolgus monkey CYP11B1 using hydroxy progesterone as substrate incubated for 120 mins by LC-MS method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Macaca fascicularis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of the Selective CYP17A1 Lyase Inhibitor BMS-351 for the Treatment of Prostate Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.61 | 5.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3780847 | — | — | 1 | 5.61 |
| CHEMBL2147041 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3780847 | — | IC50 | = | 2460.0 | nM | 5.61 |
| CHEMBL2147041 | — | IC50 | > | 7500.0 | nM | - |