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Assay Detail

CHEMBL3784451

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Physicochemical
Antioxidant activity assessed as DPPH free radical scavenging activity treated with 5% DMSO after 50 mins
15
Total Activities
15
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Physicochemical
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

The cysteine releasing pattern of some antioxidant thiazolidine-4-carboxylic acids.
Önen Bayram FE, Sipahi H, Acar ET, Kahveci Ulugöl R, Buran K, Akgün H.
Eur J Med Chem (2016) 114 : 337 -344
PubMed 27017266 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 15 4.43 4.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL863 CYSTEINE 4.0 1 4.74
CHEMBL3781865 1 4.53
CHEMBL3781802 1 4.42
CHEMBL3781641 1 4.42
CHEMBL3781315 1 4.41
CHEMBL154191 1 4.34
CHEMBL3780917 1 4.33
CHEMBL3781761 1 4.21
CHEMBL3780565 1 -
CHEMBL577683 1 -
CHEMBL3780297 1 -
CHEMBL3780051 1 -
CHEMBL3781515 1 -
CHEMBL3781828 1 -
CHEMBL146 BUTYLATED HYDROXYTOLUENE 2.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL863 CYSTEINE IC50 = 18400.0 nM 4.74
CHEMBL3781865 IC50 = 29500.0 nM 4.53
CHEMBL3781802 IC50 = 37700.0 nM 4.42
CHEMBL3781641 IC50 = 38300.0 nM 4.42
CHEMBL3781315 IC50 = 39000.0 nM 4.41
CHEMBL154191 IC50 = 45200.0 nM 4.34
CHEMBL3780917 IC50 = 46800.0 nM 4.33
CHEMBL3781761 IC50 = 61700.0 nM 4.21
CHEMBL3780565 IC50 - -
CHEMBL577683 IC50 - -
CHEMBL3780297 IC50 - -
CHEMBL3780051 IC50 - -
CHEMBL3781515 IC50 > 1000000.0 nM -
CHEMBL3781828 IC50 - -
CHEMBL146 BUTYLATED HYDROXYTOLUENE IC50 - -